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Old 02-21-2014, 11:58 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
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mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

I'll look this up for new info.

As far as I know today.... Depakote (another anti-seizure drug) has been shown to deplete carnitine in vivo.

Now, some actions of anti-seizure drugs, like Vit D and folate interference are all lumped up together for some reason. But not all of them equally affect those either. So is hair loss etc.

The Depakote/carnitine thing has been documented a long time ago, and even has caused deaths. But then that was BEFORE gabapentin and Topamax arrived to replace Depakote.

I'll look around today sometime, but this interaction is NOT in the reference I use. Gabapentin is listed but says: "no interactions" as of 2002 when it was printed. It takes time for the reports to make it medline and PubMed though. I don't expect that the information you found is accurate. If you can PM me the location of where you read it, that would help.
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