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Old 02-23-2014, 08:22 AM
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Join Date: Feb 2014
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Quote:
Originally Posted by Panorama View Post
My neurologist prescribed 50 mg Trazodone tablets, one before bedtime.

Be careful with Ambien. It has recently added a specific warning against using it with MG.

-Mark-
Thank You for Sharing!

I am trying to find the safest possible sleep aid for my debilitating insomnia. Trazodone is definitely a top contender!

"Trazodone's potent α1-adrenergic blockade (about threefold lower relative to 5-HT2A) may cause some side effects like orthostatic hypotension and sedation. Conversely, along with 5-HT2A antagonism, it may underlie its efficacy as a hypnotic. This seems possible as trazodone's antihistamine activity is relatively weak and probably clinically insignificant; hence, it cannot explain trazodone's sleep-inducing/enhancing effects. Trazodone lacks any affinity for the mACh receptors, so does not produce anticholinergic side effects."
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