Quote:
Originally Posted by anagirl
Thank you so much Tupleo - i really appreciate your help!
I just haven't sat down to spend enough time learning how to read my info on 23andme. So i just reviewed the page which show my Parkinson's data - I do not have the LRRK2 mutation, I'm GG. But I do have some issues (red marks) with the other genes - SNCA, MAPT, PARK16, BST1. It's all very interesting!
I have an appointment with my neurologist next month, so I will discuss it with him. Thanks again for all of your help!  |
You're very welcome Ana.
The commonly measured SNP for the SNCA mutation is
rs356219 . The risk allele is
G. The SNCA gene is part of the PARK family of genes associated with PD. At least 18 different mutations in SNCA have been found. The SNCA mutation has be positively linked to early-onset PD (YOPD).
By the way, the new PPMI genetic study is also recruiting people (both with and without PD) who have tested positively for the SNCA mutation. As it is rarer than LRRK2, they are only looking for 50 subjects.
Gary