I can't take prednisone - bad reaction. I had IVIG once but had aseptic meningitis (diagnosed with lumbar puncture) and now 2 neurologists says that based on those results, I am no longer a candidate. I take 200 mg Imuran daily. Dr tried to increase to 250 but I had severe anemia. I take 180 mg of mestinon in the morning and follow with 150 to 180 every 3 hours (sometimes more often). I see Dr Weiss in St Petersburg - previous Neuro was afraid to do anything but I was in bad shape. This works for me but like most here, I was afraid of taking too much. It's been almost a year at this dosage and the Dr is right. I was diagnosed over 30 years ago. I know when I have too much and my Dr understands how experienced I am with this. I can increase or decrease as needed. Don't suffer - talk to your Dr about your dosage.