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Old 03-15-2014, 06:12 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Here is a paper that explains this problem in more detail:

http://www.hindawi.com/journals/jos/2012/323061/

The serotonin reuptake inhibitors were not really studied in depth
(or those studies have been withheld by the drug companies) when they went on the market.

Because serotonin is a biogenic amine which in the body does many jobs, there are potentials for problems and side effects which only now come to light.
The obvious ones on the GI system (since serotonin is a neurotransmitter in the gut) were first listed because they are so common. But the effects on bleeding (on the platelets) were only discovered as post marketing events. This new information on bone modeling is similar.

Here is an article explaining most of the actions of serotonin in the body:
http://www.medicalnewstoday.com/articles/232248.php
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Last edited by mrsD; 03-15-2014 at 06:38 AM.
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