The autoimmune diseases tend to cluster. So if you have Hash.. you might have another.

Until your appointment, just when you see the blue toes, gently put them in lukewarm water, and see if they resolve. Do some experiments within your comfort levels to see 1) how long they are blue..2) if warmth reverses the color blue, 3) if your toes go very white often, 4) does this happen when you are hungry, and may be low blood sugar related? ... or 5) is there no trigger obvious or rhyme or reason? Things like this...details before your next doctor visit.

This link gives general info...but may not be pertinent to your specific issue:
http://www.nlm.nih.gov/medlineplus/e...cle/003215.htm

There is a condition connected to overuse of Tylenol...it changes the hemoglobin in the blood and creates a blue tint. But it would be a general effect and not confined to the toes.

I did know a gal when I was in art school, and her lips would get blue alot.... and she took HCTZ daily too. I always wondered if that drug was causing, it, because she is in her late 70's now and still alive...so the blue lips were not an ominous sign of lung or heart disease (she was in her 50's then).

Make sure you drink enough water and your blood is not too thick due to dehydration.

There is a condition sometimes connected to thyroid disease (hypo forms) called mucinosis -- which is a deposition of mucin in the tissues.
http://dermnetnz.org/immune/mucinoses.html
Presentation of this varies from person to person.