Nerve pain is all about "sensation."

It can run on a spectrum from hypersensitive to numb.

You know how if you fall asleep on your arm, it tends to go numb? The circulation has been cut off and, therefore, the nerve is, too.

When someone is paralyzed, they have no sensation. If they were to recover any sensation (as some people do), it might be an ever so slight feeling coming back, meaning they can sort of feel when someone is touching a limb.

Pain is a part of the healing process of any nerve, like when you have nerves cut into during a thymectomy! As they heal, the pain (and numbness) is reduced.

B12 can help heal peripheral nerves. And a B12 deficiency can cause peripheral nerves to hurt, be hypersensitive, numb, tingle, etc.

It doesn't necessarily mean that you have MS. Or ALS. It could be a pinched nerve, a deficiency, an electrolyte/fluid imbalance, a thyroid disease, and a lot of other causes!

Electrolyte deficiencies, like calcium, can cause all kinds of twitching.

Does that help?

Being a seronegative MGer isn't fun. But don't doubt a diagnosis if you truly believe you have it. It doesn't mean you can't have something else, but let your doctor figure it out (if they can!).

Annie