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Old 03-23-2014, 10:27 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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The link I gave has information about absorption of oral in pernicious anemia patients. They were tested too.

It works for them as for others. That is because some B12 can be absorbed PASSIVELY without intrinsic factor.

It is not common to have study subjects for vitamin research. Measuring blood levels, etc to show that passage of the nutrient does occur is costly and just not done. But today we have the data from this B12 study, and also one for magnesium.

The magnesium study showed very dramatically that OXIDE forms of magnesium remain in the bowel, and therefore now are being sold OTC as a result by Phillips company, as a laxative only.

Here is the link showing the table including the pernicious patients.
http://www.ncbi.nlm.nih.gov/pmc/arti...able/T1/#TF1-4

Look carefully at this table...The far right hand column represents the pernicious anemia and other malabsorption patients, and at 1000mcg they absorbed 12 mcg and the normals 13mcg.

Manufacturers of the various supplements rarely provide this type of data. (The data from RX drugs does provide absorption and also in more detail, which costs mega bucks ). There is one other example we at PN forum know about and that is the data on absorption of the r-lipoic acid solubilized (NaRALA) provided by that manufacturer compared to the old racemic form of alpha lipoic acid that has been around for 20+ yrs which is poorly soluble in the aqueous environment of the human GI tract. This example is only about 2 yrs old...and only a few manufacturers at this time are providing to consumers this new improved type.

So while one can still choose injections, it might be best to have the methylcobalamin in that option as well. This typically still is done at compounding pharmacies, and needs refrigeration in that form.

So I think we are quite lucky to have access to this one study by a doctor published to read and help in making decisions.
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"Thanks for this!" says:
AnnieB3 (03-23-2014)