Stacy,

I hope you are doing better. I saw on your post that you feel niacin was your trigger for this. I recently read that excess niacin (B3) is metabolized by methylation and thus uses up methyl groups. So if you have an issue with under methylation and are lacking in methyls, then niacin could have further depleted them. Restoring them may help if this is the case.

I hope you get back on track soon and get some relief.