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Old 04-07-2014, 11:06 AM
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Dr. Smith Dr. Smith is offline
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Dr. Smith Dr. Smith is offline
Senior Member (**Dr Smith is named after a character from Lost in Space, not a medical doctor)
Dr. Smith's Avatar
 
Join Date: Oct 2010
Location: Lost in Space
Posts: 3,515
10 yr Member
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Quote:
Originally Posted by Lewie View Post
I was just thinking this morning at 3:00am when I was awake that if only they made a time release melatonin.... Well apparently they do and I didn't know about it. I will definetly llok for it. The problem with melatonin for me is that it only lasts 4 hours and it loses its affect after abit.
I thought of you yesterday as well. I was doing some reading/research about L-tryptophan, and came across this...
Quote:
Mol Cell Biochem. 2004.
Tryptophan taken orally can convert into serotonin and melatonin
Tryptophan was given to a group of rats at 8 am in the morning, and to another group of rats at 8 PM at night. Four hours after administration, researchers measured the blood and brain fluid levels of serotonin and melatonin. During daytime administration, tryptophan raised the levels of serotonin. Interestingly, when tryptophan was given at night, serotonin levels did not increase, but melatonin levels increased significantly. Therefore, the serotonin that was generated by tryptophan administration was being converted into melatonin.
http://www.raysahelian.com/tryptophan.html
emphasis mine

See also: Effect of orally administered L-tryptophan on serotonin, melatonin, and the innate immune response in the rat

And FWIW... the reason I thought of you was the melatonin/sleep thing—not the rats.

Doc
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Dr. Zachary Smith
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Dr. Smith is NOT a medical doctor. He was a character from LOST IN SPACE.
All opinions expressed are my own. For medical advice/opinion, consult your doctor.
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"Thanks for this!" says:
ginnie (04-07-2014)