I tend to think its all a crapshoot whether or not one will progress and if the DMDs are really working. No one can really give you a definite answer either. And, lesion load doesn't equate to disability either. It's such an individual thing and each of us is different with the same label - MS.

I have not been on a DMD for a few years now. I don't notice a difference other than i am not have severe allergic reactions from taking C. My rate of flares hasn't changed either. I'm still averaging 2 a year. Of those flares, I still have the same amount of lesions. It's the same lesions causing me trouble over and over.