The parent company has a flashy website with virtually nothing on it.
I have my take on its validity here:
http://neurotalk.psychcentral.com/sh...ight=B12+patch
post #6
Their testing to see if it works? 6 people! Whup Whup. This is NOT a clinical trial:
Quote:
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A small clinical trial was conducted in August 2003. Six volunteers ( 4 male and 2 female between 20-48) had a baseline blood sample. A B-12 Patch was placed behind the ear of each volunteer after the baseline sample was taken.
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It is more like an experiment!
Water soluble drugs are difficult to formulate into patches... I don't see this
little company doing it.... search the parent company... the sites are all superficial.
Here is another study on oral effectivenss:
Quote:
1: Fam Pract. 2006 Jun;23(3):279-85. Epub 2006 Apr 3.Click here to read Links
Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency: a systematic review of randomized controlled trials.
* Butler CC,
* Vidal-Alaball J,
* Cannings-John R,
* McCaddon A,
* Hood K,
* Papaioannou A,
* Mcdowell I,
* Goringe A.
Department of General Practice, Cardiff University, Wales, UK.
BACKGROUND: Vitamin B(12) deficiency is common, increasing with age. Most people are treated in primary care with intramuscular vitamin B(12). Several studies have reported equal efficacy of oral administration of vitamin B(12). OBJECTIVES: We set out to identify randomized controlled trial (RCT) evidence for the effectiveness of oral versus intramuscular vitamin B(12) to treat vitamin B(12) deficiency. METHODS: We conducted a systematic review searching databases for relevant RCTs. Outcomes included levels of serum vitamin B(12), total serum homocysteine and methylmalonic acid, haemoglobin and signs and symptoms of vitamin B(12) deficiency. RESULTS: Two RCTs comparing oral with intramuscular administration of vitamin B(12) met our inclusion criteria. The trials recruited a total of 108 participants and followed up 93 of these from 90 days to 4 months. In one of the studies, mean serum vitamin B(12) levels were significantly higher in the oral (643 +/- 328 pg/ml; n = 18) compared with the intramuscular group (306 +/- 118 pg/ml; n = 15) at 2 months (P < 0.001) and 4 months (1005 +/- 595 versus 325 +/- 165 pg/ml; P < 0.0005) and both groups had neurological responses. In the other study, serum vitamin B(12) levels increased significantly in those receiving oral vitamin B(12) and intramuscular vitamin B(12) (P < 0.001). CONCLUSIONS: The evidence derived from these limited studies suggests that 2000 microg doses of oral vitamin B(12) daily and 1000 microg doses initially daily and thereafter weekly and then monthly may be as effective as intramuscular administration in obtaining short-term haematological and neurological responses in vitamin B(12)-deficient patients.
PMID: 16585128 [PubMed - indexed for MEDLINE]
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I Googled this patch again... spammers have been very active putting it out in many popular venues. Buyer beware. Remember... this is an OTC nutrient....no data of effectiveness is logged anywhere with studies or the FDA to assure you are getting anything out of that patch. Patch technology is very complex, and expensive.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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