I have to admit, that I did NOT associate you with the other board. Although the name did ring a bell, I hadn't put it together until I went back to the Sjogren's board and saw your post there...and had an, ah ha, moment. I felt I little stupid for not picking up on it sooner.
With the Cushing's, it changes how your body responds. It would be interesting to see if you received steroids before that first dose. And what the doctor has to say about your response.
Yes, Sjogren's can cause inflammation...to include neuro inflammation in some people. Just like antibody markers, not everyone tests positive even when inflammation is present. I have known inflammation (confirmed through biopsy or other procedures), yet standard labs don't always reflect it. I have no idea why