It's just such a crummy disorder...chronic depression feels like a rain cloud constantly over your head...the world's affairs don't seem to help.
I've tried many different ADs, all with side effects. I give it months to work, but it doesn't seem to help.
Behavioral therapy helps a lot though. Mind is the builder, and if one can work on reshaping how one thinks, it can make the rain cloud of depression a bit smaller, IMHO.