i understand about having depression. i've had it a long time and went thru the same thing about trying different meds. they start you on a low dose, then work up, then you have to give it wks to see if it works. if not, you start again.

however, when you find the one that works your mental world will open up.
i found journaling helped me get out my feelings. i also had cognitive therapy which really helped along with my med. i feel very well now and have for a long time. don't give up. you sound very level headed. it sounds like you monitor your condition well and work well with your dr. that's a good thing.

i would also get a copy of the mri report and start a medical file on yourself.
imho i think it's a good idea to see a neurologist, or an MS specialist, just to evaluate your mri (lesions). it never hurts to get a 2nd opinion.

and, don't let your drs tell you it's all depression, or hormones...get the answers you need. you are your own best advocate. and, take a friend or family member to the appt with you for a 2nd set of ears.

please let us know how you are.