All,

I have Idiopathic PN of both feet, but I keep searching for an answer while trying to control things. I used to take Gabapentin 1800 mg/day but had intolerable constipation. I switched to 1200 mg per day of Gralise (i.e., extended release Gabapentin) for 18 months now, and I have few side effects.

For a long time (I can't recall how long) I've had a mild sour taste in my mouth, with no other GERD symptoms. Recently, I started having intense heartburn.

Given that GERD is a common reaction to Gabapentin, and my history of troubles with it, I can't discount the possibility my body is reacting to the Gralise.

I'm not sure and am wondering, have others had sudden reactions to a drug they've been on for some time, particularly Gabapetin/Gralise?