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Old 05-12-2014, 09:54 PM
Tupelo3 Tupelo3 is offline
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Join Date: Mar 2013
Location: New Jersey
Posts: 832
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Tupelo3 Tupelo3 is offline
Member
 
Join Date: Mar 2013
Location: New Jersey
Posts: 832
10 yr Member
Default Recent MM open-label study

Quote:
Originally Posted by ginnie View Post
Good information provided. The information about Israel is correct too. They are doing the leading research on all aspects of MM. Seems to me they are years ahead of the USA. We need to get vocal and vote in the US. This choice should not be controlled by Gov. but that is what we have to deal with.
Keep posting information as you get it Brian. ginnie
Don't recall if this study was previously posted. It was open label, so could be some placebo effect. Nevertheless, it's certainly interesting.


OBJECTIVE:
The use of cannabis as a therapeutic agent for various medical conditions has been well documented. However, clinical trials in patients with Parkinson disease (PD) have yielded conflicting results. The aim of the present open-label observational study was to assess the clinical effect of cannabis on motor and non-motor symptoms of PD.
METHODS:
Twenty-two patients with PD attending the motor disorder clinic of a tertiary medical center in 2011 to 2012 were evaluated at baseline and 30 minutes after smoking cannabis using the following battery: Unified Parkinson Disease Rating Scale, visual analog scale, present pain intensity scale, Short-Form McGill Pain Questionnaire, as well as Medical Cannabis Survey National Drug and Alcohol Research Center Questionnaire.
RESULTS:
Mean (SD) total score on the motor Unified Parkinson Disease Rating Scale score improved significantly from 33.1 (13.8) at baseline to 23.2 (10.5) after cannabis consumption (t = 5.9; P < 0.001). Analysis of specific motor symptoms revealed significant improvement after treatment in tremor (P < 0.001), rigidity (P = 0.004), and bradykinesia (P < 0.001).
CONCLUSIONS:
There was also significant improvement of sleep and pain scores. No significant adverse effects of the drug were observed. The study suggests that cannabis might have a place in the therapeutic armamentarium of PD. Larger, controlled studies are needed to verify the results.

http://www.ncbi.nlm.nih.gov/pubmed/24614667
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"Thanks for this!" says:
ginnie (05-13-2014), lab rat (05-13-2014), Lemonlime (05-16-2014)