I used to suffer debilitating MS fatigue. (Mainly it was during an exacerbation,
but sometimes between flares too. When I stopped taking the MS modulating
drugs, and started LND(Low Dose Naltrexone), my debilitating mental and
physical fatigue stopped. I still get extra tired, if and when I do to much.
Doing too much, with MS, is a lot less than what "normal" peeps can do.

I do not take any "upper" drugs, as they make my heart go pitty pat!!