Well Possumtrot nothing i have tried has reduced the swollen ankles sad to say. Water pills, elevation, ice, cold water,tens and i do exercize and walk through the pain. In my case the swelling makes my feet hurt much worse. The neurologist that i see said it is common for people with PN and based on a few threads and posts here and other places its definitely not uncommon. The reason that they swell as far as i gather is that the electrical signals slow down further on damaged nerves in the heat resulting in blood vessels not reacting correctly and fluid builds up, but like i said water pills did nothing for me. Cankles...haha i like that. Wish I had some answers for you, i look at my ankles and feet sometimes and think to myself they have to be someone else's.