I really appreciate you folks sharing some insight from your experience with Tramadol. Can any of the long time users (primarily Tramadol only users for pain) tell me about how long a certain daily doseage worked for you before you felt the need to increase dosage to receive the same relief. I'm almost 65 and would hope that if I decided to switch to the Tramadol only route, I wouldn't have to worry about weaning off it before I croak. LOL. I also have taken Tranxene (a benzo) for anxiety for panic/anxiety for most of my adult life, and go thru about 25 lowest dose tabs a month presently, but not on every day (1-2 will do me for the day when I need them). Wish I didn't need it at all, but it's been a miracle drug for me.

I probably should emphasize that the drugs I've taken, Nortriptyline and Gabapentin worked well for all pain, for a short time. I don't use gabapentin anymore, but the Nortyrip still relieves the burning, pins and needles, etc. but doesn't do anything anymore for the "folded sock pain" which is the pain I feel around the front edge of the balls of my feet. I tested the Tramadol out for a couple of days, and it does dull the FS pain, but I am afraid it will also "crap out" if my body gets used to it. And although a benzo is given to those getting Serotonin Syndrome, I am also very anxious (nervous) about taking them together.