Tramadol has to be activated by the liver, to its active metabolite.
This can take up to 2-3 hours depending on the person.
So therefore tramadol is NOT fast... like tylenol or Aleve.
Some people lack the enzyme in the liver to activate tramadol, and therefore for them, it is not a good choice for pain.
Codeine (an opiate) is also metabolized to morphine by the liver, and is slower acting therefore as well.
For me, Tramadol takes about an hour to work. But it also lasts a long time for me too...into the next day, when I take it at bedtime.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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