just my perspective, there is current gdnf research and trials, most of the long term pd'ers on this board are very aware of GDNF and past trials. that's maybe why you see so few responses to your posts, it's not "news" and is also somewhat controversial because of AMGEN. We can all try to get into current and future GDNF trials. Since the first GDNF trials many more options are being explored that might reverse the symptoms but i don't think anyone is going to use infusion pumps into the brain, i could be wrong.