Is anyone taking sinemet ER or CR (is there a difference?) during the day instead of regular sinemet or stalevo? How much good time do you get with er/cr compared to regular sinemet? It is my understanding that regular sinemet has a half life of 1 hr, stalevo 2 hrs and the er's 4 hrs? (if you don't eat).
My wife takes one or two 100/25 er during the night and 4 stalevo 75mg, 4 stalevo 100mg during the day. That's about 900mg of l-dopa a day. Her neuro does not want her to exceed more than 800mg/day and to take only one er at bedtime. My wife has a lot of off time swings and tends to have bad, disturbing hallucinations into the evening. Stalevo is probably a contributor to the psychosis. Does it make sense to replace the stalevo with sinemet ER? Or, what is the down side to ER/CR?