Well your GUESS would be wrong. It's pretty easy to find if you have done the research. It doesn't sound like you have. In actuality "The exact mechanism by which the constant frequency stimulation pulse affects nearby brain cells has not been determined." It is NOT KNOWN how DBS affects nearby brain cells. If you did the research why are you guessing?

The "theory" of how it works is also unproven. DBS is believed to compensate for abnormal activity caused by loss of the dopamine producing cells. If you are still in early stages then you do not have this abnormal activity. There is no proof nor is there any evidence that treating a condition (including this one) that does not yet exist would protect you from it. This is akin to taking antibiotics all the time and hoping not to catch a bacterial infection. The side effects would be prohibitive.

I don't know of any conditions where treating for the condition would cause protective situations. If that were true we could all be treated for cancer to prevent getting it. This makes about as much sense as the idea that eating animal kidneys makes your kidneys strong. Sure it might work but it's nothing more than a guess. Would it be worth undergoing chemo to possibly not get cancer? Not for me.

A large portion of DBS failures are attributed to selection of inappropriate candidates. To be a good candidate one must have a broad spectrum of symptoms which early progression people do not have. "Findings from a retrospective analysis of DBS failures attributed more than 30% of treatment failures to DBS placement in individuals who were not optimal candidates for surgery." Patients need to have advanced pd complicated by motor fluctuations, dyskinesias, or tremor.

"CONCERN EXISTS that operating on individuals earlier than 5 years increases the risk of operating on people with atypical PD." Meaning those kinds that do not progress or misdiagnosed etc. This was my original concern. And there are other significant concerns. "An increased rate of suicide in patients undergoing STN DBS for PD has been reported."

It appears there are some very real concerns that would preclude early operations. Even though on time is usually increased the risks, problems, and deaths are higher with DBS groups than with medication only groups in large studies.

"Despite the improvements seen in the DBS treatment group, the rate of serious adverse events was significantly higher when compared to the best medical therapy group (40% vs. 15%, respectively). Two deaths occurred in the DBS group. One death was due to a cerebral hemorrhage 24 hours following lead implantation." This was one death that would not have happened without DBS.

Additionally "The most common serious adverse event in the DBS group was infection at the surgical site. An increased risk of falls and dystonia was also more common in the DBS group. Additionally, when compared to baseline, participants in the DBS group demonstrated mildly diminished performance on several measures of cognitive function at follow-up. These diminished performances were seen in measures of working memory, processing speed, verbal fluency, and delayed recall."

My feeling is that possible death, stroke, disability, diminished brain function, suicide, diminished intelligence and ability are not a good risk vs reward payoff for a person who has very mild symptoms that are well controlled with medication for many years.

Additional risks
Skin Erosion: Patients undergoing DBS are at risk for skin erosion around areas where the hardware is protruding, which may cause tension of the overlying skin. Skin erosion may also occur around the surgical incision sites. Skin erosion can present as erythema, pain, scabs, and pruritus.32 Untreated skin erosion can lead to infection of the surgical hardware and potential removal of all of the DBS hardware, depending on the site and severity of skin breakdown

Infection: Infection of the DBS surgical site or hardware may result in removal of the DBS system. Hardware infections commonly manifest with erythema and drainage. DBS patients should report any symptoms of possible infection immediately so that timely measures can be taken to prevent serious complications.

I had horrible issues when I took agonists. If you have the same issues with DBS you are stuck with it in a more permanent way. "As noted previously, behavioral changes may occur in some patients following DBS, Even in those without presurgical behavioral issues, depression, anxiety, hypomania, apathy, personality changes, and aggression can occur.39 Impulse control disorders (analogous to those associated with dopamine agonist use) may also manifest after DBS implantation, and may include pathologic gambling, hypersexuality, punding (i.e., repetitive, purposeless behavior), and spending.40-42 Awareness and monitoring for possible behavioral changes are crucial during long-term management, particularly in light of findings of increased suicide following DBS surgery."

The additional risks of death, seizures, stroke, stroke symptoms (weakness, slurred speech, numbness, worse dyskinesia, infection, breakage of leads, removal of all hardware due to infection and the list goes on. No way would any of these risks have been worth it to me. If you can read that list and think it could work for you you are more optimistic than I could ever be.