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Old 06-13-2014, 11:54 PM
johnt johnt is offline
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Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
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Welcome back, Laura!

Conductor71 references comments on the AD work. Comment 8 by Esteban is:
"Or what if the immunomodulator is a peroxynitrite scavenger?"

OK, so the paper is about AD, BUT regarding Parkinson's:

A group in Iran write [1]:

"Our data indicate that elevated serum levels of NO and peroxynitrite have an impact on progression of PD. Levels of NO and peroxynitrite may be considered as biomarkers for PD progression in the future. However, other studies are necessary for definite recommendations."

References:

[1] Eur Rev Med Pharmacol Sci. 2013 Apr;17(7):964-70.
"Nitric oxide and peroxynitrite serum levels in Parkinson's disease: correlation of oxidative stress and the severity of the disease."
Kouti L1, Noroozian M, Akhondzadeh S, Abdollahi M, Javadi MR, Faramarzi MA, Mousavi S, Ghaeli P.
http://www.europeanreview.org/wp/wp-...ds/964-970.pdf

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
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Conductor71 (06-15-2014), lab rat (06-14-2014), Tupelo3 (06-14-2014)