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Old 06-15-2014, 09:54 PM
Tupelo3 Tupelo3 is offline
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Join Date: Mar 2013
Location: New Jersey
Posts: 832
10 yr Member
Tupelo3 Tupelo3 is offline
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Join Date: Mar 2013
Location: New Jersey
Posts: 832
10 yr Member
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Quote:
Originally Posted by pegleg View Post
Amantadine helped control my dyskinesias somewhat, and mine can be so bad (and painful) that I would welcome anything! However, after my second week on Amantadine, my legs and feet swelled painfully and I had to stop the Amantadine.

Does anyone know if the "new and improved" Amantadine has similar side effects?
Or does anyone know of something else that might be causing the swelling of my lower extremities? I take Sinemet, Comtan, Requip as my regular Parkinson's regime.
Peggy
Peggy, I have a copy in my office of a presentation Adamas gave on the results for the Phase 2/3 EASED study recently completed. I focused on the efficacy results when I reviewed it and don't recall specific mention of that side effect. I'll take another look at it tomorrow. I've been using amantadine for two years with out any side effects at all. It definitely helps reduce my hand tremor.

Gary
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