Self-medicating with alcohol—or anything else—can be a very slippery slope. Eventually, two or three drinks will turn into three or four (tolerance), then four or five.... Or combining alcohol with the tramacet is a very bad idea. Tramacet is tramadol with acetaminophen (Tylenol, APAP, paracetamol). Mixing alcohol with tramadol is bad enough, but mixing acetaminophen with alcohol alone does a double whammy on your liver & kidneys.

The effect of alcohol on your PN may be a worthwhile observation, but one I would share/discuss with your doctor, who may have some ideas about better (safer) alternatives.

Doc