I have had problems for the past 10 years and have been diagnosed CIS.

I just had a repeat brain mri and a cervical spine mri. From what I can read on the report the brain is still clear but the cervical spine has several lesions. These join the 'numerous' thoracic spinal lesions I have.

I have been on Avonex for almost 10 years.

No relapses but I am getting progressively worse in my walking, strength and coordination. Have a permanently numb feeling in my left foot as if it would be swollen but it isn't.

My doctor who is an ms specialist says I am a 'hard' case to figure out. He just did a boatload of bloodwork looking for muscle diseases and mg. I think my last nmo test came out negative a few years ago. He insists I am not PPMS. I think maybe I am SPMS?

I have low B12 and get monthly B12 injections. I also take 5000 iu of vitamin D3 daily since I had low vitiamin D.

Anyone else out there in the same situation? Any thoughts? I just would like some answers on what is destroying my body and shrinking my life.