Marie I take 150 benfotiamine and 150 r-lipolic stabilized a day. On Lyrica I had periods of brain fog where I felt mentaly numb , periods of depression and sudden attacks of fatigue. I wanted it to work so badly I stayed on it too long and had a terrible time with withdrawl. I was told by neuros at Mayo Clinic it was SFN. When I asked my rhumotoligst about supplements he , said some people they seem to help, they aren't going to hurt you , so give them a try. I have reduced pain with them for sure. good luck