Do you mean back pain related sciatica? Tell us more about your situation. Ozone therapy was something I came across and looked at because I was told my peroneal branch of the sciatic nerve in my lower leg was injured when I had surgery to repair the tendon probably from the block they gave meto numb the leg. First make sure you have a complete neurological work up. I unfortunately had to go to New York to a specialist in peripheral nerves before I ever was properly evaluated. Chances are your situation is very different. Neuropathy has many causes and after seeing all the testing the New York neurologist did, there is no doubt in my mind that most people never have this. I hope you are able to find the answers you need. Interested in hearing more from you. Good luck.