Heather, what you describe is apparently not that rare, and may be par for the course.

low dose naltrexone pain got worse

You might also search the archives for threads/posts about LDN (I'd search for naltrexone).

It's also not uncommon to go through a "honeymoon period" with many new medications (e.g. gabapentin, pregabalin) as our bodies become accustomed to their presence, and/or build up to therapeutic levels.

When given any new prescription, I think it's prudent to do our own research to find out about potential adverse effects, side effects, etc., and learn which ones to ride out and/or which ones to discontinue use and call our doctors.

Doc