I take Paxil. I think that's in the same category with Zoloft? I know when I first started taking it I felt hyper and actually had to start with only 10mg and slowly work my way up. I now take 30mg a day. I was up to 60mg back in about 2005, but I started getting really bad migraines, the kind where you just want to die! I am also bi-polar and it is the only thing I can tolerate. I tried Zoloft and I wanted to jump out a window. I have an unusual sensitivity to most medicines, prescription and over the counter and vitamins. I also worry about taking a stimulant because sooner or later you end up needing more, like pain medicine.