If your insurance company tries to stick you with a huge copay, be sure to call the manufacturer of the med first to see if they have an assistance program. When United Healthcare decided to jack my copay for Rebif from $50/month to $913/month with no notice, I was able to get assistance from Rebif to keep my premium from going up at all. UHC has since tried to screw me over a couple of other ways to get me off of Rebif, but I have managed to stay on it and have a manageable copay.