I recently started 600 MG of gralise and was having some good days. Asked my neuro to up it by giving me 300MG. She said to take one in a.m. The other in p.m. I was miserable with twitches and buzzing feeling all day until it went out of my system. She told me to go back to gabapentin 300 x2. The feeling from gralise was horrible. Those of you with neuropathy can understand the feeling of electricity going thru the body. Difficult to explain to non sufferers