Pulsing in this case is using until you don't
Have the "benefits " so obvious anymore.

I stop then and wait a couple weeks or so
And restart. I think some metabolic systems
Get full or stop when the substrate is too high.
It is a form of tolerance.

Taking a vacation is a sort of "reset" so
The benefits continue. It is possible that
Ribose is not designed to be consumed
In high amounts everyday.

I just know that this happens with me
And it is a very subjective feeling.