Big thanks Mrs D and Marlene.
Yes, I think we can all agree that Mrs. D deserves vacations.
"3000mg a day is also higher than the 2000 mg"
Yes, I was surprised the amount of was so high (a dose of 1,000 mg three times per day. They state this was based on earlier studies success.
"You can look up the authors however and See if they are supported by big Pharma Or other monies. "
The list of people and institutions involved is quite lengthy, which makes me think there would be less bias (other than the general big bias towards big pharma) but perhaps I am naive.
Quote:
Originally Posted by Marlene
[I]I don't think you will ever find a good, solid research for this. It's too costly, and too difficult to design a study ...
My husband's PN is chemo induced and he has benefitted greatly from what we've learned here. ... I found that everything I learned here, could also be applied to his healing after treatment.
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Yes, thanks for these thoughts.
Even though this study was about taking ALCAR during chemo, I am still spooked because it highlights that we just don't know the mechanism of chemo neuropathy and so maybe we just don't really know if this helps or hurts.
I think of Hypocrities great advice to doctors "DO NO HARM" ... meaning at least don't make the situation worse.
Here's a quote from the study:
"... we found that at 24 weeks, there was a significant detrimental effect of the ALC intervention ..."
"Several other clinical trials of nutritional supplements that showed promise in preclinical and observational studies were found to be detrimental in clinical trials."
I found this to be true with other things I was on the verge of taking and then later found it, it actually made the situation worse or helped cancer cells grow.
Perhaps once you've just gone through ovarian cancer, one becomes skittish and extra cautious.
Another quote from study:
"Use of complementary medicine, particularly antioxidant sup- plements, is widespread among patients with cancer.27 Among 663 participants in the Long Island Breast Cancer Study who completed follow-up interviews, 401 (60.5%) reported using antioxidants during adjuvant treatment, and of these, 278 women (69.3%) used high doses.28 Americans spend $12 billion per year on dietary supple- ments.29 This is of particular concern, given the paucity of evidence of benefit and the increasing evidence of harm."
This is a good point .... Antioxidants can be tricky and can actually do the opposite of what you want depending on how taken ... especially during chemo.