I have major sensitivity on the insteps (tops of the feet). Also, can't stand anything pushing against my toes so pantyhose are out. Even socks can throw me in to agony.

I've been wearing Crocs for about 4 years. That's it, summer and winter. They're extremely lightweight, soft, and very comfy. They also come in lined versions for winter wear. In fact, Crocs brand has expanded their line of footwear to include all kinds of styles.

I also found that wearing mens shoes (I'm female) helps some, even with the Crocs. They're made larger/higher in the instep area. I have high insteps on top of it all.

Socks, I've found that buying the diabetic type helps a *lot*. They still bother me if the shoe pushes them against my toes but much better than regular socks.