I've been taking this combination for a number of years with no issues. True, I'm on the lowest dose of Cymbalta one can take without dividing up the capsules. I also seldom take more than 150 mgs total of Ultram (Tramadol) a day.

I'm limited in what I can and cannot take. I have no insurance, can't work, can't get disability. My docs simply throw meds at my symptoms. Though with PN I think that's the majority of treatment anyway.

As I've said before, I can't take the most common drug given for PN: Neurontin. It made me suicidal. So I'm kind of stuck. I tried the B12 and other supplements listed here and had no change. I just plug along hoping and praying Va will get off its butt and expand Medicaid. That's my only hope. Or wait a few more years and then try for disability going back against my late husbands social security.

If and when they expand medicaid I might finally be able to get the testing done I so desperately need. Even then, it may still be idiopathic. sigh