Quote:
Originally Posted by mamafigure
1. I went to the neuro last week. He gave me the balance test (you know, trying to get you off balance). i have always done well, but fell twice this time. I am wonderingif I may have fullblown PD now (still don't have cogwheeling and stiffness, but seem to have all other sx that I remember).
2. I have been recovering very slowly from surgery. I was only sleeping 1-5 hrs per night of broken sleep. He is having me tested for narcolepsy, but gave me remeron to take at bedtime. (He also rescinded my permission to drive).
He left the room to check for drug interractions; returned and said that there were no problems. I have been taking it since Thursday. The half life is 37 hours. Each day I am more tired and weaker. I checked and found a moderate interaction between remeron and mirapex involvin CNS and Resp. system.
Yesterday I went on a walk of about 400 feet. It took me about half an hour to get back. By the last 200 feet or so I was only moving my feet 3 or 4 inches, I was to tired to keep my eyes open, and my head drooped.
Last night I had problems breathing when I went to bed.
The neuro's nurse told me to quit taking the remeron for tonight and that she would ask the dr tomorrow.
Questions
1. What are the c hances that I have full blown PD instead of parkinsonism?
2. Has anyone else had a reaction between remeron and mirapex
Thanks,
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yes you are correct -mirapex and remeron do not mix -
Interactions between remeron (mirtazapine) and Mirapex (pramipexole)
mirtazapine and pramipexole (Moderate Drug-Drug)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be made aware of the possibility of additive CNS effects (e.g., drowsiness, dizziness, lightheadedness, confusion) and counseled to avoid activities requiring mental alertness until they know how these agents affect them. Patients should also be advised to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
please call your pharmacist tell him to tell you about the breathing problems and she/ he will look it up, they may call your doctor for you if yoiu have scripts at the pharmacy... do call your doctor, or have a loved one call for you...
http://www.drugs.com/drug-interactio...ex_d04145.html