--that my 100mg R-lipoic acid dosage SOMETIMES produced a little acid sensation, but I was taking it on an empty stomach early in the mornings.

What I decided to do was split the dose into two--50mgs early in the morning and 50mg at night before dinner. That seems to mitigate the problem somewhat.

What I don't know is if different brands of R-lipoic might have different effects in this realm; I've only ordered it from Swanson for quite a while and use their house brand. Anyone have any comparative information from trying different brands?