Here's the comment from one of our researchers:

Due to the structure of native curcumin, the consensus in the research community is that it will enter and accumulate in the human brain as easily as it does the mouse brain. Of course almost all of our interest in plant-based substances comes from epidemiological, ethnobotanical and animal studies. Human clinical studies are just too expensive and the brain makes it even more challenging. Don't forget, these are predictions, not claims. We use the machine learning algorithms and network analyses to make predictions based on available data. As the data improves, so do the predictions.