Originally Posted by mrsD

People who cannot methylate their nutrients derived from food, will suffer deficiency even when tested (showing "normal").... since the inactive forms show up in testing, floating around doing nothing for you.

The folic acid in vitamins and our fortified foods, is not active in the body. If you have the mutation, you will not get much benefit from it.

One of the treatments for PN is Metanx... a medical food with 3 activated forms of B12, folic acid and B6.