Hi Raj! Hope the Tecfidera slows down the frequency of the ON attacks, or (fingers crossed) stops them completely.

I've been on Tecfidera since Summer. Only side effect I've had is a flushing (reddening) of the face and sometimes upper body, which may or may not be accompanied by a sunburned feeling. For me, each side effect event lasted maybe 20 - 30 minutes, and went on for maybe 3 months (lessening over that time).

This, coming from someone who very rarely is affected adversely by any medication. I did 3 years of Avonex with no flu-like symptoms, which can have some people laid up for days.

Because I wasn't having flare ups before, I cannot say whether the Tecfidera is working for me or not. I just hope it keeps flare ups from ever occurring, or if I'm Secondary Progressive (which I but not my neuro believe), keeps me from getting worse. I'm still very active, driving, hiking, some slow jogging.