and of course the alternative is to use the HINZ protolcol sold by one or more of the authors?

i haven't read the whole article yet but my impression was that prior to carbidopa, l-dopa had to be taken in such large amounts, up to 12 grams, that it was not taken by many people.

of course this gets into the whole system of determining cause of death, more people could be dying from pd just because diagnosis has gotten better, a change in determining cause of death .

i think the better measure is do pd'ers live longer on avg after the addition of carbidopa to l-dopa?