I don't know the mechanism behind your return of symptoms but I have read about pot and PCS. The therapeutic doses were very small, not enough to create a high. Plus, they only worked for specific symptoms, not as a broad based treatment. I don't remember what symptoms they helped with. Some research has suggested that something that causes mild relaxation can be helpful. Again, not enough to create a high or buzz.

It sounds like your brain is very sensitive to chemicals. Likely, your sensitivity causes inflammation.