Originally Posted by zanpar321

Candida

Another important exposure route to toxic acetaldehyde levels is through its production by the opportunistic yeast, Candida albicans. In small numbers, this yeast may be kept in check in the gut by the immune system and friendly bacteria such as Lactobacillus sp. and Bifidobacterium sp. But in many people, increasing carbohydrates, especially sweets, will cause chronic Candidiasis. Candida produces acetaldehyde in the GI tract by sugar fermentation. The typical American diet along with drug and antibiotic therapies, hypochlorhydria (low stomach acid), chronic stress, environmental toxins, etc. have altered gut integrity and immunity and predisposed millions of people to yeast overgrowth or the “Candida Syndrome.”4 A person with this condition who also drinks beer, wine or liqueurs not only produces acetaldehyde from the alcohol but also delivers more sugar for yeast production of acetaldehyde, creating a double-barreled dose. Acetaldehyde produced in the gut can eventually reach more parts of the body, flooding the system and increasing the risk for damage.

Acetaldehyde and Nutrient Deficiencies

In addition to its toxic effects, acetaldehyde induces deficiencies of nutrients used for its detoxification. As an example, vitamin B1 (thiamine) is depleted through alcohol and acetaldehyde detoxification.16 B1 is essential in carbohydrate metabolism for energy production, of which the brain uses 20 percent. Acetaldehyde-induced B1 depletions exacerbate the already low B1 levels common in the population due to diuretics and other drugs, over-consumption of simple carbohydrates (dysglycemia) and adrenal stress. In addition to its many functions, thiamine, the “nerve vitamin,” is critical to nerves and neurotransmitters.

A solution to aldehyde poisoning?

Acetaldehyde Relief

Acetaldehyde toxicity can be acute or chronic. In order to stop this toxicity, levels of key nutrients that metabolize and clear acetaldehyde must be adequate. Some of these nutrients are cofactors to the enzymes that metabolize acetaldehyde and others, such as sulfur-containing compounds, are necessary to scavenge or “mop up” any stray un-metabolized acetaldehyde. Supplementation with specific nutrients offers an important level of prevention and protection from toxicity. In one animal study, pretreatment of the animals with B1, vitamin C and the sulfur-containing amino acid cysteine completely blocked the LD-90 dose of acetaldehyde (the dose that would normally kill 90 percent of the animals).



http://www.vrp.com/digestive-health/...-must-detoxify