Hello

I am new and I have been diagnosed with small fiber neuropathy via skin biopsy (ankle and thigh).

It is thus far idiopathic. The tests I have had done thus far are:

MRI brain/head-normal
paraneoplastic evaluation-negative
b12-normal
celiac-negative (had all different antibody tests done, plus biopsy)
ANA-negative, 3 times
Sjorgen's-negative
fasting glucose-runs high 70's to 80's
A1C always around 5.2
Amyloid workup and biopsy-negative
liver and kidney function-perfect
cardio work up-fine
Lyme-negative
Thyroid-I do have hypoT-but it is well controlled, and my complete thyroid labs come back fine
CBC and CMP-all good
CRP/ESR-all normal
IGM/IGG/IGA?monoclonal causes-negative
I have not taken any of the known drugs/meds that cause neuropathy (looked them up on this site and other neuropathy sites)
have not yet been evaluated for metals or genetic causes

The only thing labs turned up was a B6 level 2 times the normal upper limit. I did take an Emergen C packet (vitamins) everyday for months by that point, but it only has 10mg of Vit b6 in it. I stopped it last week when I was told about my B6 levels. I suppose it is a possible cause.

I have yet to get an EMG/NVD test, that will probably be next, so I don't know if I just have small fiber or if there is more.

I deal with burning skin (pretty much everywhere), and slight redness with it (no swelling. I also get pins and needles feelings, stocking/glove feeling, twitching. This all began back in June-so 6 months or so.

One off thing, is I have noticed my skin (especially hands, feet, eyelids) has become really transparent-I can see my veins like a roadmap. The veins aren't protruding-just much more visible.

Has anyone noticed skin or vascular changes? I am doing my best not to be scared. I am only 34, so this is a lot to take in, and of course the fear of it getting worse is hard to deal with. I know this is a long post-but it feels nice to talk to people who understand. My husband and I wanted to buy a house and have a baby-and now I don't even know what I'm going to be capable of at this point.