Hi, Sadieci. Do you have any circulatory issues that you know of? Heart issues?

Are you on any drugs (other than Mestinon)?

Cramps and spasms are not a primary symptom of MG, but they are a secondary one. And so is pain, as doctors are now admitting!

When athlete's, dancer's, or weight lifter's muscles become weak from overuse, they can cramp or spasm. MGers muscles just do that far faster.

My chest wall muscles cramped up and went into spasm right before my MG crisis. That was the only time I've experienced it in those muscles, but I've had it in others. After my crisis, I was holding a mirror with my left hand, putting makeup on. The hand contorted so badly that I momentarily thought I might be having a stroke! I hadn't been able to squeeze the urgent care doctor's fingers before being admitted to the hospital, and it hadn't gotten much better yet.

If I walk too much, my calves and feet will cramp up, usually between Mestinon doses.

Unless you have blood tests (electrolytes) when the symptoms are present, you might not "catch" them in the act. They often don't test for magnesium in a regular chem panel, so check your labs for what was done.

Hormones can cause all sorts of issues as well. Have you consulted with an endocrinologist?

If you had your B12 tested, being in the "normal range" does not necessarily mean that it's normal, especially if you have symptoms of a deficiency.

I hope you get some answers soon to all that's going on!

Annie