I believe the max recommended effective dosage of Mirapex is 4.5 mg per day so your wife has some way to go.

The advantage of an agonist alongside L-dopa is that it helps to reduce the amount of L-dopa needed, hence delaying the onset of L-dopa related side effects (however substituting them for the agonist's side effects, ho hum).

Remember as CS says, we are all different, all respond differently to the drugs. Our rate of progression is individual.

Don't look for a timetable as you won't find one, live each day and stay as low as possible on the meds for as long as you can.

Take care,
Neil.