Here is a link to a site with side effects listed that were documented by the FDA. (many are not even reported however)
http://www.drugcite.com/?q=prempro
As you can see... the risk of breast cancer is enormous.
If I were you I'd stop taking it. I don't think you even need to titrate down. You may need a several month wash out period to see changes in your side effects.
If you decide to not use Prempro again, I'd research bioidentical hormones with a specialist in your area, instead.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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